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Tory leadership candidate Dame Priti Patel has been kicked out of the race after the first vote by party MPs.
The former home secretary was running to replace Rishi Sunak against five other candidates, but fell at the first hurdle by coming in last place in the ballot.
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Ex-immigration minister Robert Jenrick topped the poll with 28 votes, followed by the widely reported favourite Kemi Badenoch on 22.
Another former home secretary, James Cleverly, received 21 votes, ex-security minister Tom Tugendhat won over 17, and the last work and pensions secretary Mel Stride gained 16.
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A total of 118 votes were cast, meaning three Tory MPs didn't have their say - with Sky News understanding one of those was Mr Sunak.
But there is still a way to go before the new leader of the opposition is crowned.
A further round of voting will take place next Monday to get the ballot down to four, and they will then face an onstage hustings during the Conservative Party conference at the end of the month.
After another vote by MPs, the wider party membership will then choose their leader from the last two standing, with the result expected to be announced on 2 November.
Posting on X after the result was confirmed, Ms Badenoch thanked her supporters, adding: "It's time to deal with hard truths today, rather than big problems tomorrow.
"I look forward to making the case for renewal around the country, with colleagues and members."
In his statement, Mr Tugendhat paid tribute to his "friend Priti" and the "good Conservatives" he is competing against.
But, he added: "Only I can deliver the Conservative revolution that our party and our nation need.
"I will lead in opposition as I would as prime minister, by serving the British people, leading with conviction, and acting to make our nation better. That is my promise, and I always deliver on my promises."
Dame Priti has been a Tory MP since 2010 and had the most experience of the candidates on the ballot.
She became a key torchbearer for the right when she served as home secretary under Boris Johnson, before being somewhat eclipsed by his successor, Suella Braverman.
But she had positioned herself as a unity candidate in this race, arguing the party should not let "a soap opera of finger-pointing and self-indulgence" distract from the goal of winning the next election.